Terminus - Exoplanet City Builder
Off the Katchup today: http://www.indiegogo.com/terminusgame
The tl;dr version of the background story is "Earth's gonna get splatted by asteroids, so you go off with some people and find a new planet".
This is one of the few crowdfunding things that has actually hooked my just from the video - it's very well put together, although as the Katchup says, there's nothing in the way of actual "game" images/video yet.
The lead dev does seem really into the whole concept, which is always nice, and the fact they have a science advisor on their team had me jumping up and down with happiness. They seem to have done plenty of planning, rather than just jumping in and coding before having any idea of their direction.
Only thing that has me concerned is that it might be a bit too niche - I certainly love the idea, but I can see how others might not be so into it.