I wouldn't. I don't feel the need to customize something if it's not going to make customizing that thing worth my while. I'm fine with games that give me one weapon and say "Go!" as long as the rest of the game is interesting. I want interesting challenges that force me to make interesting decisions--tactical, narrative, or what-have-you. ME1 didn't give me interesting choices or challenges with it's weapon system. I'd as soon not have to bother. It makes me feel like the darn game is assigning me busy work to meet some kind of arbitrary quota of Things Wot Must Be Clicked For This To Be a Proper Video Game.
I'll take a bad weapon system (ME1) over no weapon system to speak of (ME2) any day of the week.